LYMPHOID NEOPLASIA microRNA-29c and microRNA-223 down-regulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification
نویسندگان
چکیده
1Laboratory of Experimental Hematology, Faculty of Medicine, Institut Jules Bordet, Université Libre de Bruxelles (ULB), Brussels; 2Functional Genomics and Translational Research Unit, Faculty of Medicine, Institut Jules Bordet, ULB, Brussels; 3Machine Learning Group, Faculty of Sciences, ULB, Brussels; 4Cliniques Universitaires Saint Luc, Service de Biologie Hématologique, Brussels; 5Center for Human Genetics, KU Leuven, Leuven; 6Department of Medical Genetics, Erasme Hospital, Faculty of Medicine, ULB, Brussels; and 7Department of Cytogenetics, Institut Jules Bordet, ULB, Brussels, Belgium
منابع مشابه
microRNA-29c and microRNA-223 down-regulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification.
Aberrant expression of microRNAs has been recently associated with chronic lymphocytic leukemia (CLL) outcome. Although disease evolution can be predicted by several prognostic factors, a better outcome individualization in a given patient is still of utmost interest. Here, we showed that miR-29c and miR-223 expression levels decreased significantly with progression from Binet stage A to C were...
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تاریخ انتشار 2009